David G. Bieling 
Member since Jan 2, 2013



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Re: “The Munchies Kill

I’m not a medical professional but must comment on this opinion piece. His line of reasoning appears to be “Phytocannabinoids stimulate the vagus nerve causing compulsive consumption of confection”. At best, this is an oversimplification of a compulsive eating disorder; at worst, it is absolutely misleading. This much is correct: the vagus nerves are stimulated by a neuropeptide (ghrelin) produced in the GI tract when the stomach is empty. Specifically, this neuropeptide stimulates vagus nerve receptors, signaling the lateral hypothalamus, initiating appetite and increasing gastric acid secretions. Obviously, the individual’s response to this stimulative process varies and there are people less affected than others. Some people develop an over-sensitive response and have difficulty controlling their food consumption, whether they use cannabis or not. Medical “pot” is clearly not integral to the story and appears to be a red herring.

Posted by David G. Bieling on 02/25/2016 at 9:09 AM

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